Stir Bar Sorptive Extraction (SBSE) is an innovative and efficient method [1] for the extraction of drugs and pharmaceuticals from blood-, urine- and tissue samples in a forensic toxicology laboratory. As shown in this application note and earlier publications [2,3,4], SBSE is an effective screening tool for drugs and pharmaceuticals in biological fluids and tissue. The SBSE technique is easy to use and the method described in this publication is performed without additional use of organic solvents, centrifugation, or the liquid transfer steps that are normally necessary when performing liquid-liquid or solid-phase extraction.

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Twister® / Stir Bar Sorptive Extraction (SBSE)

The GERSTEL Twister® enables efficient extraction of organic compounds from aqueous matrices based on Stir Bar Sorptive Extraction (SBSE). SBSE is a solvent-free extraction technique, which is significantly faster than most conventional extraction techniques. SBSE is up to 1000x more sensitive than SPME since the stir bar has significantly more sorbent volume and since it can extract, and concentrate analytes from, a much larger sample volume due to the efficient stirring.

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