Description
This task is easily possible when you add the GERSTEL LC/MS Effluent Optimizer (LEO) module to your LC/MS/MS system. Application examples show sensitivity gains of up to a factor of 40 by simply adding a salt solution to the LC effluent and/or changing its pH. The LEO module is quickly and easily installed in your LC/MS system. A solvent mixture, buffer solution or reagent is then easily added to the effluent ensuring that the LC separation can be performed under optimal conditions while also enabling maximum yield in the MS ionization process, helping to reduce or eliminate Ion Suppression. Whether you are looking to perform pH adjustment or post-column derivatization, for method development or routine analysis, when you use LEO you can easily and efficiently control all parameters as part of the overall software method. Just one sequence table controls the entire system from sample preparation through LC separation and effluent optimization to MS analysis. It is all done with the click of a mouse.
