The Opioid Epidemic continues to increase throughout the United States. According to the CDC, 66 % of all drug overdose deaths in 2016 involved an opioid [1]. This calculates to roughly 116 deaths every day from opioid related overdoses. After becoming addicted to prescription opioids, users may unfortunately turn to illicit alternatives such as heroin.…
Packaging materials for foodstuffs or consumer usage must not alter the fl avor or odor of the substance being packaged. Examples of packaging materials include the paper used to wrap cigarettes, the paper cartons used in orange juice or milk and the Polyethylene (PE) often used for caps to seal soft drink bottles. Sometimes, due…
Analysts often encounter complex real-world sample types such as petroleum fractions or volatile polymer components. Resolving all individual compounds using a single chromatographic separation can be quite challenging. Coupling columns with different polarities (multidimensional GC) can signifi cantly improve the resolution of complex samples. We coupled two low thermal mass (LTM) GC column modules with…
The quality of packaging materials used in the food and beverage industry must be controlled regularly in order to avoid negative effects on packaged products caused by emissions, e.g. VOC emissions from printing processes or from varnishes used on inner surfaces of the packaging material. Many companies have worldwide production sites, that may not all…
Direct thermal extraction is a sensitive technique for the analysis of residual compounds in solid matrices such as polymers, films, powders, and fibers. This approach can be used for both qualitative identification of unknowns as well as quantification of trace components. Quantification of analytes is often performed based on off-line spiking of liquid or gaseous…
This paper describes an automated pyrolysis system for gas chromatography (GC) based on a filament type pyrolyzer combined with a commercially available thermal desorption instrument, onto which the pyrolysis module is installed. Automated sample introduction for both pyrolysis and thermal desorption is performed using a commercially available autosampler. For pyrolysis of solid, liquid, or melting…
This application note describes two automated methods for screening of extractable compounds from materials for food packaging, medical or technical purposes. The first method is based on automated liquid extraction performed by the GERSTEL MultiPurpose Sampler (MPS), the second involves thermal desorption of the material in question in the GERSTEL Thermal Desorption Unit (TDU). Both…
The analysis of airborne aldehydes and ketones first involves collection of the analytes by passing air through a cartridge containing 2,4-dinitrophenylhydrazine (DNPH). As the air passes through the cartridge, the analytes react with the DNPH to form hydrazones which are immobilized on the cartridge. The cartridges are then eluted with solvent and the DNPH derivatives…
IV bag components were analyzed for extractables using direct thermal desorption/thermal extraction combined with a unit mass resolution GC/MSD system. The results were compared to those obtained for leachables by stir bar sorptive extraction of an aqueous simulant stored in the exact same type of IV bag, again combined with GC/MS determination of the leached…
Rubber particles, sometimes derived from used tires, are used on artificial turf athletic fields, on playgrounds and as mulch. These particles can off-gas and leach compounds into the environment and may present a contact or inhalation hazard. Recent news reports in the US and Europe indicate a growing concern regarding potential health effects in athletes…
The influence of variations in desorption temperature, desorption fl ow and sample preparation on VDA 278 analysis method [1] robustness and reproducibility is studied using a wide variety of samples from automobile interior materials: polypropylene (PP) granulate, polyurethane (PU) foam, leather, Duroplastic plastics and paint. It is shown that a temperature difference of just two…
An automated analysis system consisting of a dynamic headspace (DHS) system coupled with thermal desorption-Gas Chromatography/ Mass Spectrometry (TD-GC/MS) was used for fully automated microscale chamber material emission analysis of Spray Polyurethane Foam (SPF). Closed-cell and opencell SPF samples were analyzed for emissions of TVOCs and high boiling compounds such as, for example, fl ame…
An automated micro-scale chamber method based on 2,4-dinitrophenylhydrazine (DNPH) derivatization and Tenax TA adsorption, for sampling formaldehyde, acetaldehyde, acetone, acrolein, as well as volatile organic compounds (VOCs) was developed. Following the sampling step, the Tenax TA tubes were immediately transferred to a thermal desorption (TD)-GC/MS system for analysis. The DNPH tubes were transferred to an…
The analysis of airborne aldehydes and ketones first involves collection of the analytes by passing air through a cartridge containing 2,4-dinitrophenylhydrazine (DNPH). As the air passes through the cartridge, the analytes react with the DNPH to form hydrazones which are immobilized on the cartridge. The cartridges are then eluted with solvent and the DNPH derivatives…
A new fully automated thermal desorption (TD)-GC/MS method was developed for determination of formaldehyde and other airborne carbonyls as well as VOCs for material emission testing. The method includes an automated in-situ derivatization agent loading step prior to every sampling step, thus blank values are avoided. Pentafluorophenylhydrazine (PFPH) was used as derivatization agent and was…
This study describes the use of the GERSTEL MultiPurpose Sampler (MPS) fitted with a Thermal Desorption Unit (TDU) and a Cooled Injection System (CIS 4) PTV-type Inlet for the automated direct thermal extraction analysis of packaging for three different brands of crème-fi lled chocolate sandwich cookies, cheese-filled sandwich crackers and soft and chewy candy. Download…
Electron Paramagnetic Resonance (EPR) measures the concentration and composition of free radicals in a sample. Samples can be either liquid, solid or gas. Free radicals are atomic or molecular species with unpaired electrons that can be highly reactive. There are also many stable free radicals, such as melanin in hair and ultramarine blue pigment. Many…
Asphaltene concentration can be easily measured by ESR once a calibration curve has been made. The calibration curve made using an asphaltene powder dissolved in toluene. The ESR spectra of the various concentrations of apshaltene powder used to make the calibration curve. Active Spectrum has software that will automatically measure the concentration of an unknown…