This application note describes two automated methods for screening of extractable compounds from materials for food packaging, medical or technical purposes.
In this report, a completely automated, 96 well plate format “Prep-and-Shoot” workfl ow including enzymatic hydrolysis, dilution and injection is described.
IV bag components were analyzed for extractables using direct thermal desorption/thermal extraction combined with a unit mass resolution GC/MSD system.
The in vitro metabolic stability of potential drug candidates is routinely examined at an early stage of drug discovery.